Pii: S0032-3861(99)00620-5
نویسندگان
چکیده
Glucose-sensitive hydrogels were prepared by the copolymerization of diethylaminoethyl methacrylate (DEAEM), poly(ethylene glycol) monomethacrylate (PEGMA) and functionalized glucose oxidase (GOD) and catalase in solution. Tetra(ethylene glycol) dimethacrylate (TEGDMA) was used as the crosslinking agent. The equilibrium and dynamic swelling properties were studied to investigate the pHsensitive swelling behavior of the gels. The effects of crosslinking ratio and enzyme content on the swelling properties were studied. The hydrogels demonstrated critical swelling behavior as the pH approached 7.0. The mesh sizes and the diffusion coefficients were determined. Dynamic swelling studies were performed and the results were analyzed using a first-order model to calculate the time constants of swelling and syneresis. Pulsatile swelling studies revealed the reversible nature of the swelling/deswelling process. q 2000 Elsevier Science Ltd. All rights reserved.
منابع مشابه
Pii: S0032-3861(99)00217-7
The dispersion copolymerization of methyl methacrylate (MMA) with macromonomeric azoinitiator, MIM-400, as a macrocrosslinker initiated by the benzoyl peroxide (BPO)/N,N 0dimethylaniline (DMA) coupled in water/ethanol (4/1, v/v) at 208C was carried out to yield PEG-b-PMMA networks with labile azo linkages in the main chain. Gel fraction, swelling ratios (qv) and the average molecular weights be...
متن کاملPii: S0032-3861(99)00651-5
This paper deals with the kinetic study of bulk free radical polymerization of styrene initiated with the commercial bifunctional initiator 2,5-dimethyl-2,5-bis(2-ethyl hexanoyl peroxy)hexane (Lupersol 256). The polymerization kinetics is investigated by DSC measurement for temperatures between 80 and 1108C and for initiator initial concentration from 0.115 up to 0.46 mol%. The experimental con...
متن کاملPii: S0032-3861(00)00617-0
Six generations of lactodendrimers based on poly(amidoamine) were studied in dilute solutions of 0.2 M NaCl by methods of molecular hydrodynamics (velocity sedimentation and viscometry) and optics (static and dynamic light scattering). Molecular weights, sedimentation and diffusion coef®cients, and intrinsic viscosity values were measured. These data were analysed and compared with previous res...
متن کاملPii: S0032-3861(00)00031-8
A model was developed to describe the overall dissolution kinetics of semicrystalline PVA gels prepared by freezing and thawing techniques. The dissolution process was described as a three-step mechanism: detachment-, diffusion-, and disentanglement-controlled dissolution. The unfolding of crystalline regions due to detachment and diffusion was calculated. The lamellar thickness of a PVA crysta...
متن کاملPii: S0032-3861(00)00817-x
In this research, hybrid materials based on poly(methyl methacrylate) and silica were synthesized via sol±gel process. Their glass transition behavior was investigated by differential scanning calorimeter. In DSC measurement, 1808C heat-treated hybrid materials exhibited higher miscibility as compared to untreated materials. Relationship between miscibility variation of hybrid materials and hea...
متن کامل